Advantages of Avibodies

  • Rapid generation from existing antibodies
  • Rapid de novo generation from affinity Bio library with pre-engineered conjugation sites
  • Greater tumour penetrance and deposition than intact antibodies
  • Exquisite target selectivity and high avidity
  • Superior targeting = improved safety and efficacy
  • No off-target deposition seen preclinically or in man (low toxicity)
  • Pharmacokinetics that can be readily modified to suit the application
  • Site-specific conjugation of payload for a fully defined product
  • Conjugation sites and chemistry consistent across products
  • Easy, inexpensive manufacture in bacterial or mammalian systems
  • Stable on the shelf and in vivo, including GMP products
  • Worldwide IP estate for proprietary surface disulphides and accurate payload loading